Kinetics of water–isocyanate reaction in N,N-dimethylformamide

作     者：Zhirong Chen Weitao Yang Hong Yin Shenfeng Yuan 

作者机构：College of Chemical and Biologlical Engineering Zhejiang University Hangzhou 310027 China 

出 版 物：《Chinese Journal of Chemical Engineering》 (中国化学工程学报（英文版）)

年 卷 期：2017年第25卷第10期

页      面：1435-1441页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 

基　　金：Supported by the Key Science and Technology Innovation Team of Zhejiang Province(2011R50007) 

主　　题：Kinetics Isocyanate Polyurethane Catalysis HPLC Kinetic modeling 

摘      要：The uncatalyzed reaction of p-tolyl isocyanate(p-TI)with water in N,N-dimethylformamide(DMF)was investigated by high performance liquid chromatography(HPLC).The reactions were carried out at different temperatures from 293 K to 323 K,using various molar ratios of water to ***,as a special amide,was proved to be an efficient catalyst for water–isocyanate *** the reaction conditions in this study,substituted urea was the only final product *** appreciable amount of intermediate p-toluidine was *** of the isocyanate group as well as the amine and urea were determined as a function of *** kinetic equations were deduced for each of the substance on the basis of a multistep mechanism,instead of a simple second order reaction as *** constants were calculated using the software ***,the effects of temperature and concentrations of reactants on the reaction rate and amine content were *** activation energy of each step was also determined.