Synergists action of piperonyl butoxide and S,S,S-tributyl phosphorotrithioate on toxicity of carbamate insecticides against Blattella germanica

作     者：Alireza Sanei Dehkordi Yaser Salim Abadi Hasan Nasirian Teymour Hazratian Mohammad Amin Gorouhi Saideh Yousefi Azim Paksa 

作者机构：Department of Medical Entomology and Vector Control Faculty of Health Hormozgan University of Medical Sciences Infectious and Tropical Diseases Research Center Hormozgan Health Institute Hormozgan University of Medical Sciences Department of Health Services and Health Promotion School of Health Rafsanjan University of Medical Sciences Molecular Medicine Research Center Rafsanjan University of Medical Sciences Department of Medical Entomology and Vector ControlSchool of Public HealthTehran University of Medical Sciences Tabriz University of Medical Sciences Department of Medical Entomology and Vector Control School of Health Kerman University of Medical Sciences Sirjan Faculty of Medical Sciences Kerman University of Medical Sciences Department of Parasitology School of Medicine Kashan University of Medical Sciences 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2017年第10卷第10期

页      面：981-986页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Blattella germanica 信仰神人协力合作说者 Bendiocarb 酉维因 

摘      要：Objective: To determine the synergists action of piperonyl butoxide(PBO) and S,S,Stributyl phosphorotrithioate(DEF) on toxicity of carbamate insecticides against Blattella germanica in Tehran city.Methods: In the current study, German cockroach strains were collected from several hospitals and dormitories in Tehran.At the beginning, different concentrations of bendiocarb and carbaryl(insecticides belong to carbamate group) were determined by surface contact on a susceptible strain.Then, the level of susceptibility and type of resistance mechanisms in the collected strains from contaminated sites to the aforementioned insecticides were studied by using PBO and DEF synergists with different insecticide ratios to synergist(1:0, 1:1, 1:2, 1:3).Results: The DEF synergist along with bendiocarb and carbaryl completely eliminated the resistance in all strains but PBO did not completely eliminate the resistance in the strains of Mofid, Alvand, Valiasr hospitals and Shariati dormitory.Generally, the impact of DEF was observed in the removing resistance more than PBO.Conclusions: In most of these strains, resistance to bendiocarb and carbaryl is completely eliminated by DEF, showing a very high role of estraze enzymes in resistance to bendiocarb and carbaryl.But in most strains PBO does not remove the resistance because other mechanisms, such as reduced cuticle penetration and insensitivity to the acetylcholine esterase enzyme, may be involved.