Nanocrystalline TiO_2-HClO_4:A novel,efficient and recyclable catalyst for the chemoselective N-Boc protection of amines under solvent-free conditions

作     者：Farhad Shirini Seyyed Vahid Atghia Mojtaba Ghazi Jirdehi 

作者机构：Department of ChemistryCollege of ScienceUniversity of GuilanRasht 41335Islamic Republic of Iran 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2013年第24卷第1期

页      面：34-36页

核心收录：

学科分类：081704[工学-应用化学] 081705[工学-工业催化] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the University of Guilan Research Council for the partial support of this work 

主　　题：Nanocrystalline TiO2 HClO4AminesN Boc protectionSolvent free conditions 

摘      要：Nanocrystalline TiO2-HClO4, as newly reported catalyst, has been used as an efficient and reusable catalyst for the chernoselective N-Boc protection of amines. The clean, mild acidity condition, quantitative yields of products, short reaction time and low reaction temperature are attractive features of this reaction. In practice, this method is a combination of a satisfactory synthesis and more significantlv easy 13roduct isolation and 13urification.