An extremely rare case of delusional parasitosis in a chronic hepatitis C patient during pegylated interferon alpha-2b and ribavirin treatment

作     者：Geert Robaeys Jozef De Bie Marc Van Ranst Frank Buntinx 

作者机构：Department of Gastroenterology and Hepatology Ziekenhuis Oost Limburg Genk Belgium Department of Psychiatry Ziekenhuis Oost Limburg Genk Belgium Laboratory of Clinical and Epidemiological Virology Department of Microbiology and Immunology Rega Institute and University Hospitals Katholieke Universiteit Leuven Leuven Belgium Department of General Practice Katholieke Universiteit Leuven Leuven Belgium and Department of General Practice Maastricht University The Netherlands 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2007年第13卷第16期

页      面：2379-2380页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Interferons Ribavirin Hepatitis C Chronic Parasitology Delusions 

摘      要：During treatment of chronic hepatitis C patients with interferon and ribavirin, a lot of side effects are described. Twenty-three percent to 44% of patients develop depression. A minority of patients evolve to psychosis. To the best of our knowledge, no cases of psychogenic parasitosis occurring during interferon therapy have been described in the literature. We present a 49-year-old woman who developed a delusional parasitosis during treatment with pegylated interferon alpha-2b weekly and ribavirin. She complained of seeing parasites and the larvae of fleas in her stools. This could not be confirmed by any technical examination. All the complaints disappeared after stopping pegylated interferon alpha-2b and reappeared after restarting it. She had a complete sustained viral response.