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文献详情 >丙硫咪唑15或30mg/(kg·d)治疗蛛网膜下腔和脑室内囊... 收藏

丙硫咪唑15或30mg/(kg·d)治疗蛛网膜下腔和脑室内囊虫病的试验

Albendazole trial at 15 or 30 mg/kg/day for subarachnoid and intraventricular cysticercosis

作     者:Góngora-Rivera F. Soto-Hernández J. L. González Esquivel D. 牛亚利(译) 

作者机构:不详 Department of Infectious Disease Instituto Nacional de Neurologa Y Neurociruga Manuel Velasco Suárez Insurgentes Sur 3877 Tlalpan 14269 D.F. Mexico City Mexico 

出 版 物:《世界核心医学期刊文摘(神经病学分册)》 (Digest of the World Core Medical Journals:Clinical Neurology)

年 卷 期:2006年第2卷第9期

页      面:9-9页

学科分类:1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主  题:地塞米松治疗 脑室内囊肿 蛛网膜下腔 丙硫咪唑 囊虫病 试验 皮质激素治疗 常用剂量 

摘      要:Thirty-six patients with subarachnoid and intraventricular cysticercosis were randomly assigned to receive albendazole at 15 or 30 mg/kg/day plus dexamethasone for 8 days. Results favored a higher dose, with larger cyst reduction on MRI at 90 and 180 days and higher albendazole sulfoxide levels in plasma. An albendazole course at 30 mg/kg/day combined with corticosteroids is safe and more effective than the usual dose. A single treatment was insufficient in intraventricular and giant cysts.

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