Mycobacterium tuberculosis in the aorta of a patient with takayasu’s arteritis. extra pulmonary tuberculosis

作     者：María Elena Soto Virgilia Soto Julia Isela Martín Sandría Ricardo Gamboa Claudia Huesca 

作者机构：不详 

出 版 物：《Health》 (健康（英文）)

年 卷 期：2011年第3卷第3期

页      面：159-161页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Takayasu’s arteritis extrapulmonary tuberculosis IS6110 and HupB sequences 

摘      要：Takayasu’s arteritis (TA), of unknown etiology, has been related with Mycobacterium tuberculosis infection. The published cases are controversial. A 29- year-old man died, prolapse of the aortic valve and unspecific arteritis were demonstrated at necropsy. Our objective was to search in the fresh aortic tissues, the infectious agent of tuberculosis through culture, as well as by performing histopathology and searching by the molecular study, sequences of genes associated to micobacteria and Ziehl’s stain. Results. The bacillus of tuberculosis was observed by the Ziehl’s stain and the sequences of insertion IS6110 gene were identified. Our findings support the relation of TA with possible tuberculosis ***. The possibility that Takayasu’s arteritis is an extra pulmonary tu-berculosis must be explored.