Optical coherence tomography of the living human kidney
作者机构：Department of BiochemistryMolecular.and Celular Biology Georgetown University MedicalCenter WashingtonDC20007USA Fischell Department of BioengineeringUriversity of Maryland College ParkMD 20742USA Colege of Photonic and Electric Engineering Fujian Normal UniversityFuzhouChina MedstarGeorgetown Transplant Inste Georgetown University Medical Center WashingtonD C 20007USA
出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)
年 卷 期：2014年第7卷第2期
页 面：88-97页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 0808[工学-电气工程] 1002[医学-临床医学] 0809[工学-电子科学与技术（可授工学、理学学位）] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 0805[工学-材料科学与工程（可授工学、理学学位）] 0836[工学-生物工程] 0702[理学-物理学] 10[医学]
主 题：Optical coherence tomography doppler optical coherence tomography acute tubularnecrosis kidney transplantation uriniferous tubules glomerulus renal blood flow
摘 要：Acute tubular necrosis(ATN)induced by ischemia is the most common insult to donor kidneysdestined for *** results from sweling and subsequent damage to cells lining thelkidney *** this study,we demonstrate the capability of optical coherence tomography(OcT)to image the renal microst ructures of living human donor kidneys and potentially providea measure to det ermine the extent of A *** also found that Doppler-based OCT(i.e.,DOCT)reveals renal blood flow dynamics that is another major factor which could relate to post-transplant renal *** OCT/DoCT oberva tions were performed in a noninvasive,sterileand timely manner on intact human kidneys both prior to(er vivo)and following(in vivo)*** results indicate that this imaging model provides transplant surgeons withan objective visualization of the transplant lidneys prior and immediately post transplantation.
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