Monte Carlo simulation based thinning and calculating method for noninvasive blood glucose sensing by near-infrared spectroscopy

作     者：Congcong Ma Jia Qin Qi Zhang Junsheng Lu Kexin Xu Jingying Jiang 

作者机构：Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments College of Precision Instruments B Opto-electronics Engineering Tianjin University(TU)92#Weijin Road Nankai DistrictTianjin 300072P.R.China San FranciscoOphthalmologyUniversity of Caliorrnia 480 North Civic Drive 106 Walnut CreekCalifornia 94596United States State Key Laboratory of Precision Measuring Technology and Instruments College of Precision Instruments Opto-electronics Engineering Tianjin University(TU)92#Weijin RoadNankai District Tianjin 300072P.R.China 

出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)

年 卷 期：2017年第10卷第2期

页      面：40-51页

核心收录：

学科分类：0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 

基　　金：the National High Technology Research and Development Program of China(863 Program:2012AA022602) the 111 Project(B07014)and Tianjin Natural Science Foundation(No.16JCZDJC31200) 

主　　题：Thinning and calculating method Monte Carlo simulation noninvasive blood glucose sensing foating reference theory positioning error light source drift. 

摘      要：Previous results show that the floating reference theory(FRT)is an effective tool to reduce the infuence of interference factors on noninvasive blood glucose sensing by near infrared spectros-copy(NIRS).It is the key to measure the floating reference point(FRP)precisely for the application of *** Carlo(MC)simulation has been introduced to quantitatively in-vestigate the effects of positioning errors and light source drifts on measuring *** this article,thinning and calculating method(TCM)is proposed to quantify the positioning ***-while,the normalization process(NP)is developed to significantly reduce the error induced by light source *** results according to TCM show that 7 purm deviations in positioning can generate about 10.63%relative error in *** is more noticeable that 1%fluctuation in light source intensity may lead to 12.21%relative ***,the proposed NP model can effectively reduce the error caused by light source ***,the measurement system for FRPs must meet that the positioning error is less than 7 purm,and the light source drift is kept within 1%.Furthermore,an improvement for measurement system is proposed in order to take advantage of the NP model.