Treatment of cutaneous lichen planus with ALA-mediated topical photodynamic therapy
作者机构：Shanghai Skin Diseases Hospital Shanghai 200050P.R.China Shanghai Skin Diseases Clinical College of Anhui Medical University Shanghai 200050P.R.China Department of Dermatology Huadong HospitalShanghai 200040P.R.China University of Colorado Denver Cancer Center and CAPT LabCOUSA
出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)
年 卷 期：2015年第8卷第1期
页 面：88-94页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：supported by grants from the National Natural Science Foundation of China (81272990) the Natural Science Foundation of Shanghai (11ZR1432800) the Key Project of Shanghai Health Bureau (A 20124034)
主 题：5-aninolevulinic acid photodynamie therapy lichen planus
摘 要：Purpose:To evaluate the efectiveness of topical 5-aminolevulinie acid(ALA)-mediated pho-todynamic therapy(PDT)for the treatment of cutaneous lichen planus(LP).Methods:A total of 17 symptomatic LP lesions in 7 Chinese patients were *** cream(10%)was applied topically to LP lesions for *** lesions were iradiated with a 635 nm diode laser at the dose level of 100J/cm^(2).The treatment was repeated at two week *** assessmnent was conducted before each ***-up was performed once a month for up to six ***:Lesions showed significant improvement after one to four courses of *** response was achieved in 13 lesions(five patients)and partial remission in four lesions(two patients).The complete response rate was 71%.There was no significant side ffects except the feeling of pain that most patients could ***-up of five patients who achieved complete response showed no signs of ***:Topical ALA PDT is effective in the treatment of cutaneous LP.
维普期刊数据库