Effect of Xinmaitong Capsule on Total Insche mia Burden in Coronary Heart Disease Patients with Myocardial Ische mia and Analysis of Its The rapeutical Mechanis m
Effect of Xinmaitong Capsule on Total Inschemia Burden in Coronary Heart Disease Patients with Myocardial Ischemia and Analysis of Its Therapeutical Mechanism出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志(英文版))
年 卷 期：2000年第2期
页 面：100-100页
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
主 题：Effect of Xinmaitong Capsule on Total Insche mia Burden in Coronary Heart Disease Patients with Myocardial Ische mia and Analysis of Its The rapeutical Mechanis m
摘 要：To assess the effect of Xinmaitong (XMT) capsule in treating ischemic cardial disease. Methods: Sixty coronary heart disease (CHD) patients with myocardial ischemia were divided randomly into two groups. XMT group (30 cases) was treated with XMT plus western medicine, and control group (30 cases) with western medicine alone. The changes of the scores for clinical symptoms,total ischemia burden (TIB),plasma endothelin (ET),nitric oxide (NO), superoxide dismutase (SOD), and the malonyldialdeyde (MDA) levels were observed before and after treatment. Results: After XMT treatment the scores of clinical symptoms, TIB, ET and MDA levels significantly decreased (P0.01), the levels of NO and SOD significantly increased (P0.01) in the XMT group, comparing with control group these changes were statistically different (P0.01). Conclusion:XMT capsule can act against myocardial ischemia effectively, one of the mechanisms of which is protecting the function of vascular endothelium and resisting lipid peroxidation injury. The effects of adding XMT capsule on conventional treatment of western medicine were better than those of using western medicine alone.
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