Onsite-effects of dual-hemisphere versus conventional single-hemisphere transcranial direct current stimulation A functional MRI study

作     者：Yong Hyun Kwon Sung Ho Jang 

作者机构：Department of Physical TherapyYeungnam College of Science & TechnologyDaegu 705-703Republic of Korea Department of Physical Medicine and RehabilitationCollege of MedicineYeungnam UniversityDaegu 705-717Republic of Korea 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2012年第7卷第24期

页      面：1889-1894页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

基　　金：supported by a National Research Foundation of Korea Grant funded by the Korean Government No.2009-0064682 

主　　题：transcranial direct current stimulation dual-hemispheric stimulation cortical activation functional MRI primary sensorimotor cortex neuroimaging regeneration neural regeneration 

摘      要：We performed functional MRI examinations in six right-handed healthy *** functional MRI scanning,transcranial direct current stimulation was delivered with the anode over the right primary sensorimotor cortex and the cathode over the left primary sensorimotor cortex using dual-hemispheric transcranial direct current *** was compared to a cathode over the left supraorbital area using conventional single-hemispheric transcranial direct current stimulation. Voxel counts and blood oxygenation level-dependent signal intensities in the right primary sensorimotor cortex regions were estimated and compared between the two transcranial direct current stimulation *** results showed that dual-hemispheric transcranial direct current stimulation induced greater cortical activities than single-hemispheric transcranial direct current *** findings suggest that dual-hemispheric transcranial direct current stimulation may provide more effective cortical stimulation than single-hemispheric transcranial direct current stimulation.