Synthesis, Structural Investigations and Biological Screening of Diorganotin(IV) Complexes Derived from 5,5-Diethyl Sodium Barbital

作     者：Wajid Rehman Amin Badshah Salimullah Khan Iftikhar Ahmad 

作者机构：Department of Chemistry Hazara University Department of Chemistry Quaid-e-Azam University Department of Pharmacy Hazara University Department of Physics Louisiana State University 

出 版 物：《Chinese Journal of Structural Chemistry》 (结构化学（英文）)

年 卷 期：2009年第28卷第4期

页      面：419-426页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Higher Education Commission of Pakistan 

主　　题：5,5-diethyl sodium barbital spectra antibacterial anti-inflammatory organotin 

摘      要：Some biologically important tin（Ⅳ） complexes derived from 5,5-diethyl sodium barbital have been synthesized and characterized through various analytical and spectroscopic techniques such as IR, ^1H-, ^13C-NMR and ^119mSn mossbauer. On the basis of these spectroscopic techniques, octahedral geometry has been assigned to all the novel compounds. These complexes, soluble in DMSO and DMF, were screened against a wide range of microorganisms. The results proved that the diphenyltin（Ⅳ） and dibutyltin（Ⅳ） complexes exhibit excellent activity against all types of microorganisms, while the rest of the compounds show significant activity that can be used during the biological study.