Incidence of cystoid macular edema after Descemet's stripping automated endothelial keratoplasty

作     者：Eduard Pedemonte-Sarrias Toni Salvador Playà Irene Sassot Cladera Oscar Gris Joan Ribas Martínez José García-Arumí Núria Giménez 

作者机构：Ophthalmology DepartmentHospital Universitari Mútua TerrassaFundació Docència i Recerca Mútua TerrassaUniversitat de Barcelona Ophthalmology DepartmentHospital Universitari Germans Trias i PujolHealth Sciences Research Institute Germans Trias i Pujol Foundation Surgery DepartmentUniversitat Autònoma de Barcelona Instituto de Microcirugía Ocular (IMO) Ophthalmology DepartmentHospital Sant Antoni Abat Ophthalmology DepartmentHospital Universitari Vall d’HebronUniversitat Autònoma de Barcelona Research UnitFundació Docència i Recerca Mútua TerrassaUniversitat de Barcelona Laboratory of ToxicologyUniversitat Autònoma de Barcelona 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2017年第10卷第7期

页      面：1081-1087页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：Descemet membrane endothelial keratoplasty Descemet stripping automated endothelial keratoplasty combined with phacoemulsification Descemet stripping endothelial keratoplasty macular edema postoperative complications 

摘      要：AIM： To determine the incidence of cystoid macular edema（CME） after Descemet＇s stripping automated endothelial keratoplasty（DSAEK）.METHODS： This study included all consecutive patients operated in a Spanish tertiary reference hospital over a period of four years. A total of 55 eyes from 47 patients matched the selection criteria. CME was diagnosed clinically at the slit-lamp and confirmed by optical coherence tomography. RESULTS： Six cases of CME were diagnosed postoperatively, which represented an incidence of 11%. Three patients had previously undergone DSAEK alone（7%; 3/41） and the other three, DSAEK combined with phacoemulsification（21%; 3/14）. Five out of six patients with CME responded to standard therapy.CONCLUSION： CME is a possible complication after DSAEK and can be treated with standard therapy. CME appears more frequently when DSAEK is combined with phacoemulsification and posterior chamber（PC） intraocular lens（IOL） implantation. Intraoperative damage to the corneal endothelial cells might play a role in the pathogenesis of CME. As long as the causes remain unclear, we recommend administering prophylaxis when risk factors are present or when combined surgery is planned.