Combination of Solid-Phase Micro-Extraction and Direct Analysis in Real Time-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Sensitive and Rapid Analysis of 15 Phthalate Plasticizers in Beverages

作     者：Mengxi Wu Haoyang Wang Guoqing Dong Brian D.Musselman Charles C.Liu Yinlong Guo 

作者机构：Shanghai Mass Spectrometry CenterShanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China IonSenseInc.999 BroadwaySuite 404SaugusMA 01906USA ASPEC Technologies LimitedRoom 1506RunFengDeShang Bldg ANo.60 An Li LuChaoyang DistrictBeijing 100101China 

出 版 物：《中国化学:英文版》 (Chinese Journal of Chemistry)

年 卷 期：2015年第33卷第2期

页      面：213-219页

核心收录：

学科分类：08[工学] 082701[工学-核能科学与工程] 0827[工学-核科学与技术] 0703[理学-化学] 

基　　金：support from National Natural Science Foundation of China(Nos.21172250 and 21275155) 

主　　题：solid-phase micro-extraction direct analysis in real time Fourier transform ion cyclotron resonance mass spectrometry phthalates 

摘      要：A method for rapid identification and quantification of phthalate plasticizers in beverages was developed.A number of 15 phthalate plasticizers which covered all the phthalates concerned in the US Consumer Product Safety Improvement Act(CPSIA),European Union legislations and Chinese national standards(GB)were *** a combined solid-phase micro-extraction(SPME)and direct analysis in real time mass spectrometry(DART-MS)approach,phthalates at sub-ng•mL^(−1)levels can be qualitatively and quantitatively analyzed in a short *** use of ultrahigh-resolving power and the accurate mass measurement capacity naturally provided by Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR-MS)minimizes the matrix interferences and thus enables the evaluation of phthalates in a complex matrix without extensive sample handlings or *** limits of quantification(LOQs)were estimated to be at 0.3-5.0 ng•mL^(−1),lower than the Maximum Residue Limit(MRL)regulated by the European Union legislations(2007/19/EC)in foods,beverages,food packaging and toys(0.3-30 ng•mL^(−1)).This rapid and easy-to-use SPME-DART-FT-ICR-MS method provided a relatively high-throughput and powerful analytical approach for quick testing and screening phthalates in beverages and water samples to ensure food safety.