A Facile Synthetic Route to New Fluorinated Building-Blocks of 1-Fluoroalkynes and 1-Fluorodiynest

作     者：刘翠波 马海 聂晶 马军安 

作者机构：Department of ChemistryTianjin UniversityTianjin 300072China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2012年第30卷第1期

页      面：47-52页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 08[工学] 10[医学] 

基　　金：This work was supported financially by the National Natural Science Foundation of China (Nos. 20972110 and 21002068) 

主　　题：electrophilic fluorination terminal alkyne terminal 1,3-diyne 1-fluoroacetylene 

摘      要：A facile and direct fluorination process of alkynes and diynes was developed, in the presence of n-butyllithium, the reaction of a series of terminal alkynes and diynes with the electrophilic fluorinating reagent （NFSI） proceeded to afford various 1-fluoroalkynes and 1-fluoro-l,3-diynes in moderate to high yields.