Evidence for using a dual COX 1/2 and 5-LOX inhibitor in neurodegenerative diseases

作     者：Natasha Irrera Alessandra Bitto 

作者机构：Department of Clinical and Experimental MedicineUniversity of Messina Messina Italy 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2017年第12卷第7期

页      面：1077-1078页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：COX LOX in Evidence for using a dual COX 1/2 and 5-LOX inhibitor in neurodegenerative diseases for 

摘      要：A complex network of factors contributes to neuroinflammation,such as infections,brain injuries and accumulation of toxic metabolites（Gendelman,2002）.Eicosanoids and several cytokines are the main mediators of inflammatory process;in fact,when an inflammatory condition persists,it can be responsible for the progression of degenerative diseases,