Conjugate Hydrocyanation of Chalcone Derivatives Using Ethyl Cyanoacetate as an Organic Cyanide Source

作     者：Zheng Li Junjun Yin 

作者机构：College of Chemistry and Chemical Engineering Northwest Normal University Lanzhou Gansu 730070 China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2017年第35卷第7期

页      面：1179-1184页

核心收录：

学科分类：081702[工学-化学工艺] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：The authors thank the National Natural Science Foundation of China (Nos. 21462038  21362034) and Key Laboratory of Eco-Environment-Related Polymer Materials of Ministry of Education for the financial support of this work 

主　　题：hydrocyanation chalcone derivative ethyl cyanoacetate organic cyanide source 

摘      要：The conjugate hydrocyanation of chalcone derivatives using ethyl cyanoacetate as an organic cyanide source at room temperature under open air and transition metal-free conditions was described. The protocol has advantages of using relatively cheap, less toxic, stable and easy-to-handle cyanating reagent, high yield, and mild reaction condi- tion.