Minimally invasive and open gallbladder cancer resections: 30-vs 90-day mortality

作     者：Naeem Goussous Motahar Hosseini Anne M Sill Steven C Cunningham 

作者机构：Department of SurgerySaint Agnes HospitalBaltimoreMDUSA 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2017年第16卷第4期

页      面：405-411页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：This study was presented at the 57th annual (2016) meeting of the Societyfor Surgery of the Alimentary Tract during the Digestive Disease Week(DDW) San Diego CA USA 

主　　题：gallbladder cancer laparoscopic minimally invasive survival radical cholecystectomy complications 

摘      要：BACKGROUND:Minimally invasive surgery is increasingly used for gallbladder cancer *** mortality at 30 days is low,but 90-day mortality is ***:Using National Cancer Database(1998-2012),all resection patients were ***-and 90-day mortality rates were ***:A total of 36 067 patients were identified,19 139(53%) of whom underwent *** age was 71 years and 70.7% were ***-day mortality following surgical resection was 2.3-fold higher than 30-mortality(17.1% vs 7.4%).There was a statistically significant increase in 30-and 90-day mortality with poorly differentiated tumors,presence of lymphovascular invasion,tumor stage,incomplete surgical resection and low-volume centers(P0.001 for all).Even for the 1885 patients who underwent minimally invasive resection between 2010 and 2012,the 90-day mortality was 2.8-fold higher than the 30-day mortality(12.0% vs 4.3%).CONCLUSIONS:Ninety-day mortality following gallbladder cancer resection is significantly higher than 30-day *** mortality is associated with tumor grade,lymphovascular invasion,tumor stage,type and completeness of surgical resection as well as type and volume of facility.