Expanding Roles of PIFs in Signal Integration from Multiple Processes
Expanding Roles of PIFs in Signal Integration from Multiple Processes作者机构：Department of Molecular Biosciences and The Institute for Cellular and Molecular Biology The University of Texas at Austin Austin TX 78712 USA Department of Biotechnology and Kumho Life Science Laboratory Chonnam National University Gwangju 61186 Korea These authors contributed equally to this article.
出 版 物：《Molecular Plant》 (分子植物（英文版）)
年 卷 期：2017年第10卷第8期
页 面：1035-1046页
核心收录：
学科分类：0810[工学-信息与通信工程] 08[工学] 09[农学] 0903[农学-农业资源与环境] 090302[农学-植物营养学] 081001[工学-通信与信息系统]
基 金：We acknowledge support by grants from the National Institutes of Health (1R01 GM-114297) National Science Foundation (MCB- 1543813) U.S.-Israel Binationat Science Foundation (BSF#2015316) to E.H. and Rural Development Administration Republic of Korea (P J01104001) to J.-I.K
主 题：circadian clock growth-defense tradeoff hormone signaling phytochrome-interacting factor ther-momorphogenesis signal integration
摘 要：PHYTOCHROME-INTERACTING FACTORs （PIFs） are members of the basic helix-loop-helix （bHLH） family of transcription factors in Arabidopsis. Since their discovery in phytochrome-mediated light signaling pathways, recent studies have unraveled new functions of PIFs in integrating multiple signaling pathways not only through their role as transcription factors directly targeting gene expression but also by interacting with diverse groups of factors to optimize plant growth and development. These include endogenous （e.g., hormonal） as well as abiotic （light, circadian, and elevated temperature） and biotic （defense responses） pathways. PIFs interact with key factors in each of these pathways and tailor the outcome of the signal integration among these pathways. This review discusses the roles of PIFs as pivotal signal integrators in regulating plant growth and development.
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