Toxicity of Chemotherapy in a Patient with Bloom Syndrome＇s Diagnosis
Toxicity of Chemotherapy in a Patient with Bloom Syndrome＇s Diagnosis作者机构：Division of Clinical Oncology University Hospital Ribeirāo Preto Medical School University of Sāo Paulo Ribeirāo Preto 14048-900 Brazil
出 版 物：《Journal of Pharmacy and Pharmacology》 (药剂与药理学（英文版）)
年 卷 期：2017年第5卷第7期
页 面：430-433页
学科分类：071011[理学-生物物理学] 0710[理学-生物学] 0832[工学-食品科学与工程（可授工学、农学学位）] 07[理学] 08[工学]
主 题：Bloom's syndrome cancer chemotherapy toxicity.
摘 要：Bloom＇s syndrome is a rare disease that is related to an increased risk of developing malignant neoplasm. The patient reported was followed up with several hospital staff when she was diagnosed with gastric cancer, but unfortunately, she had already peritoneal implants in moment of the surgery approach. It has been reported in the literature that patients with this syndrome present greater toxicity to the chemotherapeutic treatment, however due to the rarity of the disease, it is not known exactly how the adjustment of these drugs should be performed and which is the better protocol to use. Palliative chemotherapy was proposed, but after receiving one dose of the initially treatment, she developed severe and limiting toxicity.
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