Rhodium(Ⅲ)-catalyzed selective access to isoindolinones via formal [4+1] annulation of arylamides and propargyl alcohols

作     者：Youwei Xu Fen Wang Songjie Yu Xingwei Li 许有伟;王芬;于松杰;李兴伟

作者机构：Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 Liaoning China University of Chinese Academy of Sciences Beijing 100049 China 

出 版 物：《Chinese Journal of Catalysis》 (催化学报（英文）)

年 卷 期：2017年第38卷第8期

页      面：1390-1398页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 0817[工学-化学工程与技术] 08[工学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the Dalian Institute of Chemical Physics,Chinese Academy of Sciences the National Natural Science Foundation of China (21525208,21472186)~~ 

主　　题：Rhodium C-H activation [4+1] annulation Propargyl alcohol Isoindolinones 

摘      要：A mild and efficient oxidative synthesis of isoindolinones has been realized by Rh(III)‐catalyzed C?H activation of benzamides and[4+1]coupling with propargyl *** coupling system proceeds with broad substrate scope and mild conditions and provides a new approach to access the useful skeleton ofγ‐lactams with a stereogenic center.