Ultrasound-guided transrectal extended prostate biopsy:a prospective study

作     者：Mohammed Ahmed Al-Ghazo Ibrahim Fathi Ghalayini Ismail Ibrahim Matalka 

作者机构：Faculty of MedicineKing Abdullah University HospitalJordan University of Science and Technology (JUST)Irbid 22110Jordan 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2005年第7卷第2期

页      面：165-169,页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：ultrasonography prostate biopsy diagnosis 

摘      要：Aim:To evaluate the diagnostic value of the 10 systematic transrectal ultrasound-guided (TRUS) prostate biopsy compared with the sextant biopsy technique for patients with suspected prostate ***:One hundred and fifty-two patients with suspected prostate cancer were included in the *** were entered in the study because they presented with high levels of prostate specific antigen (PSA) (over 4 ng/mL) and/or had undergone an abnormal digital rectal examination (DRE).In addition to sextant prostate biopsy cores,four more biopsies were obtained from the lateral peripheral zone with additional cores from each suspicious area revealed by transrectal ***,lateral peripheral zone and suspicious area biopsy cores were submitted separately to the patho- logical ***:Cancer detection rates were 27.6 % (42/152) and 19.7 % (30/152) for the 10-core and sextant core biopsy protocols,*** the lateral peripheral zone (PZ) to the sextant prostate biopsy showed a 28.6 % (12/42) increase in the cancer detection rate in patients with positive prostate cancer (P0.01). The cancer detection rate in patients who presented with elevated PSA was 29.3 % (34/116).When serum PSA was 4-10 ng/mL TRUS-guided biopsy detected cancer in 20.6 %,while the detection rate was 32.4 % and 47.0 % when serum PSA was 10-20 ng/mL and above 20 ng/mL,***:The 10 systematic TRUS-guided prostate biopsy improves the detection rate of prostate cancer by 28.6 % when compared with the sextant biopsy technique alone,without increase in the *** therefore recommend the 10-core biopsy protocol to be the preferred method for early detection of prostate cancer.