Ⅰ型假性醛固酮减少症患者的皮损临床病理分析

作     者：Martn J.M. Calduch L. Monteagudo C. 阎小宁 

作者机构：Servicio de Dermatologa Hospital Clnico Universitario de ValenciaAvenida BlascoIbanez 1746010ValenciaSpain 

出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)

年 卷 期：2005年第1卷第9期

页      面：18-19页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：常染色体隐性 红粟 外分泌腺 收敛剂 机能紊乱 遗传型 靶器官 

摘      要：The autosomal recessive form of type I pseudohypoaldosteronism (PHA-1) is an unusual disorder characterized by aldosterone resistance at the target organs, which leads to an excessive loss of sodium chloride through urine, sweat and saliva, among other secretions. Such a high concentration of salt in the sweat during the depletive crises directly causes inflammation and damage in the eccrine structures, with cutaneous lesions similar to those appearing in miliaria rubra. We report an autosomal recessive PHA-1 in a 4-year-old girl, with cutaneous lesions mimicking miliaria rubra, that improved after treatment with astringent solutions and avoidance of profuse sweating.