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Primary intestinal lymphangiectasia with generalized warts

Primary intestinal lymphangiectasia with generalized warts

作     者:Soon Jae Lee Hyun Joo Song Sun-Jin Boo Soo-Young Na Heung Up Kim Chang Lim Hyun 

作者机构:Department of Internal Medicine Jeju National University School of Medicine Department of Pathology Jeju National University School of Medicine 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2015年第21卷第27期

页      面:8467-8472页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Protein-losing enteropathy Lymphocytopenia Cell-mediated immunodeficiency Primary intestinallymphangiectasia Warts 

摘      要:Primary intestinal lymphangiectasia(PIL) is a rare protein-losing enteropathy with lymphatic leakage into the small intestine. Dilated lymphatics in the small intestinal wall and mesentery are observed in this disease. Laboratory tests of PIL patients revealed hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia and increased stool α-1 antitrypsin clearance. Cell-mediated immunodeficiency is also present in PIL patients because of loss of lymphocytes. As a result, the patients are vulnerable to chronic viral infection and lymphoma. However, cases of PIL with chronic viral infection, such as human papilloma virus-induced warts, are rarely reported. We report a rare case of PIL with generalized warts in a 36-year-old male patient. PIL was diagnosed by capsule endoscopy and colonoscopic biopsy with histological tissue confirmation. Generalized warts were observed on the head, chest, abdomen, back, anus, and upper and lower extremities, including the hands and feet of the patient.

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