Comparison of Intraarterial VS with Intravenous Heparin Delivery in Maintaining Microvascular Patency

作     者：王玉新 

作者机构：Department of Plastic and Maxilofacial Surgery The Affiliated Stomatological Hosp China Medical University Shenyang China 

出 版 物：《中国医科大学学报》 (Journal of China Medical University)

年 卷 期：1990年第19卷第S1期

页      面：66-71页

核心收录：

学科分类：10[医学] 

主　　题：microvascular thrombosis heparin 

摘      要：Utilizing a reliable, reproducible arterial inversiongraft thrombosis model, comparison of intraarterial VSwith intravenous heparin delivery in maintaining micro-vascular patency has been finished, concentrated on thestudy of the effective mechanism of heparin. Vesselpatency, complication rate and representative electromi-croscopy section of the AIG were studied. Patency inthe intraarterial group is 90% (26/29) as compared to50% (12/26) in the intravenous delivery group(P0.05).Scanning electromicroscopy showed a significant absenceof dense fibrin deposition and decrease in the numberof aggregated platelets in the intra-arterial perfusedAIG. The results of the present study indicate that thesmall dose of heparin through the artery is still effectivein maintaining the vessel pateney. Furthermore, in alarge, carefully controlled series, the complication ratewas low.