Preparation of imprinted monolithic column under molecular crowding conditions

作     者：Xiao Xia Li Xin Liu Li Hong Bai Hong Quan Duan Yan Ping Huang Zhao Sheng Liu 

作者机构：College of Pharmacy Tianjin Medical University Tianjin 300070 China Basic Medical Research Centre of Tianjin Tianjin Medical University Tianjin 300070 China These authors contributed equally to this work. 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2011年第22卷第8期

页      面：989-992页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(No.21075090) the Natural Science Foundation of Tianjin(No.08JCYBJC02000) 

主　　题：Molecularly imprinted polymer Monolithic column Enrofloxacin Molecular crowding 

摘      要：Molecular crowding is a new concept to obtain molecularly imprinted polymers（MIPs） with greater capacity and *** this work,molecular crowding agent was firstly applied to the preparation of MIPs monolithic column.A new polymerization system based on molecular crowding surrounding was developed to prepare enrofloxacin-imprinted monolith,which was composed of polystyrene and *** result showed that the monolithic MIPs under molecular crowding conditions presented good molecular recognition for enrofloxacin with an imprinting factor of 3.03.