Miktoarms hyperbranched polymer brushes:One-step fast synthesis by parallel click chemistry and hierarchical self-assembly

作     者：HAN Yi & GAO Chao MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering,Zhejiang University,Hangzhou 310027,China 

作者机构：MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and Engineering Zhejiang University Hangzhou China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2010年第53卷第12期

页      面：2461-2471页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(50773038 & 20974093) National Basic Research Program of China(973 Program)(2007CB936000) the Fundamental Research Funds for the Central Universities(2009QNA4040) Qianjiang Talent Foundation of Zhejiang Province(2010R10021) the Foundation for the Author of National Excellent Doctoral Dissertation of China(200527) 

主　　题：miktoarms molecular brushes hyperbranched polyglycerol amphiphilic self-assembly 

摘      要：Spherical molecular brushes with amphiphilic heteroarms were facilely synthesized by grafting the arms of hydrophobic 2-azidoethyle palmitate and hydrophilic monoazide-terminated poly(ethylene glycol) onto the core of alkyne-modified hyperbranched polyglycerol (HPG) with high molecular weight (Mn=122 kDa) via one-pot parallel click *** parallel click grafting strategy was demonstrated to be highly efficient (～100%),very fast (～ 2 h) and well controllable to the amphilicity of molecular *** adjusting the feeding ratio of hydrophobic and hydrophilic arms,a series of brushes with different arm ratios were readily *** resulting miktoarms hyperbranched polymer brushes (HPG-g-C16/PEG350) were characterized by hydrogen-nuclear magnetic resonance (1H NMR),Fourier transform infrared (FT-IR) spectroscopy,gel permeation chromatography (GPC),and differential scanning calorimetry (DSC) *** spherical molecular brushes showed high molecular weights up to 230 kDa,and thus could be visualized by atomic force microscopy (AFM).AFM and dynamic laser light scattering (DLS) were employed to investigate the self-assembly properties of amphiphilic molecular brushes with closed proportion of hydrophobic and hydrophilic *** brushes could self-assemble hierarchically into spherical micelles,and network-like fibre structures,and again spherical micelles by addition of n-hexane into the dichloromethane or chloroform solution of *** addition,this kind of miktoarms polymer brush also showed the ability of dye loading via host-guest encapsulation,which promises the potential application of spherical molecular brushes in supramolecular chemistry.