Hyaluronidase in sub-Tenon's anesthesia for phacoemulsification,a double-blind randomized clinical trial

作     者：Mohammadreza Sedghipour Ali Mahdavifard Rohollah Fadaei Fouladi Davoud Gharabaghi Mohammadbagher Rahbani Ghasem Amiraslanzadeh Mohammadreza Afhami 

作者机构：Department of OphthalmologyTabriz University of Medical SciencesNikookari Eye HospitalTabrizIran Department of OphthalmologyTabriz University of Medical SciencesAlavi Eye HospitalTabrizIran Department of OphthalmologyTabriz University of Medical SciencesImam Reza HospitalTabrizIran 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2012年第5卷第3期

页      面：389-392页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：hyaluronidase local block sub-Tenon's anesthesia 

摘      要：AIM:To investigate the effect of hyaluronidase use on the quality of sub-Tenon s anaesthesia for phacoemulsification.· METHODS:This was a randomized,double-blind clinical trial which was conducted at Nikookari Eye Hospital for 5 ***-two eyes of candidates for phacoemulsification under sub-Tenon s anaesthesia were randomly allocated to two equal groups and received either 2 mL of lidocaine 2% solution with(LH),or without(L) addition of hyaluronidase(150IU/mL).Akinesia was assessed 15 minutes after sub-Tenon s *** and surgeon s satisfaction,as well as the postoperative pain(the visual analogue scale,VAS) were investigated after *** contingency tables(including the Chi-square or Fisher s exact tests,when appropriate) and parametric analysis(the independent samples t test) were used for statistical analysis.· RESULTS:Complete akinesia(33.3% vs 4.8%,P =0.04),as well as the patients(85.7% vs 57.1%,P =0.04)and surgeon s satisfaction(87.5% vs 52.4%,P =0.02) were significantly more frequent in LH than in L *** mean VAS was significantly lower in the same group(1.90±1.45 vs 3.00±1.55,P =0.04).· CONCLUSION:Addition of hyaluronidase to lidocaine solution for sub-Tenon s anesthesia significantly improves the ocular akinesia,enhances the intra-operative patients and surgeons satisfaction,and attenuates the postoperative pain.·