Hyaluronidase in sub-Tenon's anesthesia for phacoemulsification,a double-blind randomized clinical trial
Hyaluronidase in sub-Tenon's anesthesia for phacoemulsification,a double-blind randomized clinical trial作者机构:Department of OphthalmologyTabriz University of Medical SciencesNikookari Eye HospitalTabrizIran Department of OphthalmologyTabriz University of Medical SciencesAlavi Eye HospitalTabrizIran Department of OphthalmologyTabriz University of Medical SciencesImam Reza HospitalTabrizIran
出 版 物:《International Journal of Ophthalmology(English edition)》 (国际眼科杂志(英文版))
年 卷 期:2012年第5卷第3期
页 面:389-392页
核心收录:
学科分类:1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题:hyaluronidase local block sub-Tenon's anesthesia
摘 要:AIM:To investigate the effect of hyaluronidase use on the quality of sub-Tenon s anaesthesia for phacoemulsification.· METHODS:This was a randomized,double-blind clinical trial which was conducted at Nikookari Eye Hospital for 5 ***-two eyes of candidates for phacoemulsification under sub-Tenon s anaesthesia were randomly allocated to two equal groups and received either 2 mL of lidocaine 2% solution with(LH),or without(L) addition of hyaluronidase(150IU/mL).Akinesia was assessed 15 minutes after sub-Tenon s *** and surgeon s satisfaction,as well as the postoperative pain(the visual analogue scale,VAS) were investigated after *** contingency tables(including the Chi-square or Fisher s exact tests,when appropriate) and parametric analysis(the independent samples t test) were used for statistical analysis.· RESULTS:Complete akinesia(33.3% vs 4.8%,P =0.04),as well as the patients(85.7% vs 57.1%,P =0.04)and surgeon s satisfaction(87.5% vs 52.4%,P =0.02) were significantly more frequent in LH than in L *** mean VAS was significantly lower in the same group(1.90±1.45 vs 3.00±1.55,P =0.04).· CONCLUSION:Addition of hyaluronidase to lidocaine solution for sub-Tenon s anesthesia significantly improves the ocular akinesia,enhances the intra-operative patients and surgeons satisfaction,and attenuates the postoperative pain.·