Cytotoxicity of the rhizome of medicinal plants

作     者：Shakhawoat Hossain Golam Kader Farjana Nikkon Tanzima Yeasmin 

作者机构：Department of Biochemistry and Molecular BiologyRajshahi University 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2012年第2卷第2期

页      面：125-127页

学科分类：1008[医学-中药学(可授医学、理学学位)] 10[医学] 

基　　金：supported by Ministry of Science Information and Communication Technology Bangladesh(grant No.12/2008-2009) 

主　　题：Cytotoxicity Zingiber zerumbet Curcuma zedoaria Bangladesh 

摘      要：Objective:To investigate the cytotoxicity of the crude ethanol extract of the rhizome of Zingiber zerumbel(***)(L)Smith,and Curcuma zedoaria(***)Rosc,against Artemia salina ***:Fresh rhizomes of ***(L)Smith,and *** Rose,were extracted separately in cold with ethanol(2.5 L)and after concentration a brownish syrupy suspension of ethanol extracts of ***(L)Smith,and *** Rose,was *** cytotoxic effect of the crude ethanol extracts of both plants was determined by brine shrimp lethality ***:Crude ethanol extracts of the rhizome of ***(L)Smith,showed the highest cytotoxicity(LC_(50)was 1.24μg/mL)against brine shrimp nauplii as compared with *** Rose.(LC_(50)was 33.593μg/mL)after 24 h of ***:It can be concluded that the rhizome of ***(|L)Smith,and *** Rose,can be used as a source of cytotoxic agent.