Antihyperglycemic effect of methanol extract of Tamarix aphylla L. Karst (Saltcedar) in streptozocin–nicotinamide induced diabetic rats

作     者：rooh ullah shafiq ahmed tariq naeem khan nawaz sharif zia ud din khalid mansoor 

作者机构：department of pharmacology institute of basic medical sciences khyber medical university 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2017年第7卷第7期

页      面：619-623页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by Institute of Basic Medical Sciences  Khyber Medical University with grant no. of 06472414 

主　　题：Tamarix aphylla leaves Diabetes Streptozotocin Antidiabetic potential Insulin secretion 

摘      要：Objective: To evaluate the antihyperglycemic potential of Tamarix aphylla(T. aphylla)leaves in STZ–NIC induced diabetes in Wister Albino ***: Acute toxicity study was done to check the toxicity of T. aphylla(L. Karst)methanol extract. T. aphylla leaves extract was administered intraperitoneally(100 mg,250 mg and 400 mg/kg body weight per day) to diabetic Wister rats for 21 days. The various parameters were studied including fasting blood glucose levels, haemoglobin and glycosylated ***: The treatment groups with the extract at three dose levels expressively abridged the intensities of blood glucose and Glycosylated Haemoglobin. The earlier detected reduced level of plasma haemoglobin of the diabetic rats was raised to near normalcy with treatment of ***: The results of the current study confirm that the leaves extract of T. aphylla are nontoxic and have antidiabetic nature.