面部肉芽肿继发于德美蒂(充填剂)微植入体:1例个案报道和注射不同的永久性填充材料引起的肉芽肿的组织病理鉴别诊断

作     者：Vargas-Machuca I. Gonzlez-Guerra E. Angulo J. L. Requena 任建文 

作者机构：Department of Dermatology Fundación Jiménez Daz Avda. Reyes Católicos 2 28040-Madrid Spain Dr. 

出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)

年 卷 期：2006年第2卷第12期

页      面：51-页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：肉芽肿 炎症 植入体 植入物 面部 永久性 德美 填充材料 继发 

摘      要：Wrinkle reduction and the correction of skin defects using injectable aesthetic microimplants are now widely performed by dermatologists and plastic surgeons. In recent years, dermal filler substances containing polymer particle suspensions such as Bioplastique, Artecoll, and Dermalive are the most commonly used materials. These microimplants are permanent, non-biodegradable, and generally well tolerated, although various adverse reactions are still possible. We describe here a patient with facial granulomas secondary to Dermalive injections for correction of naso-labial folds and wrinkles. The particular shape of the injected particles allows for correct identification of the implanted material. Therefore, histopathologic examination is the best means to obtain the correct diagnosis of foreign body granuloma and to identify the type of filler particles. We discuss the histopathologic differential diagnosis among the granulomas secondary to the most commonly used aesthetic permanent filler materials.