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Potential Mechanisms Underlying the Therapeutic Effects of Electroconvulsive Therapy

Potential Mechanisms Underlying the Therapeutic Effects of Electroconvulsive Therapy

作     者:Jiangling Jiang Jijun Wang Chunbo Li 

作者机构:Shanghai Key Laboratory of Psychotic DisordersShanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghai Jiao Tong UniversityShanghai 200030China Bio-X InstitutesKey Laboratory for the Genetics of Developmental and Neuropsychiatric DisordersMinistry of EducationShanghai Jiao Tong UniversityShanghai 200030China Brain Science and Technology Research CenterShanghai Jiao Tong UniversityShanghai 200030China 

出 版 物:《Neuroscience Bulletin》 (神经科学通报(英文版))

年 卷 期:2017年第33卷第3期

页      面:339-347页

核心收录:

学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基  金:supported by the grants of Shanghai Hospital Development Center,China(SHDC12014111) the Science and Technology Commission of Shanghai Municipality,China(14411961400 and 13dz2260500) the Shanghai Health System Leadership in Health Research Program,China(XBR2011005) 

主  题:Electroconvulsive therapy Neurotransmitters Neurotrophins Inflammatory factors Epigenetics Neuroimaging 

摘      要:In spite of the extensive application of electroconvulsive therapy(ECT), how it works remains *** far, researchers have made great efforts in figuring out the mechanisms underlying the effect of ECT treatment via determining the levels of neurotransmitters and cytokines and using genetic and epigenetic tools, as well as structural and functional neuroimaging. To help address this question and provide implications for future research, relevant clinical trials and animal experiments are reviewed.

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