Low frequency repetitive transcranial magnetic stimulation improves motor dysfunction after cerebral infarction

作     者：Zhi-yong Meng Wei-qun Song 

作者机构：Department of RehabilitationXuanwu HospitalCapital Medical University 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2017年第12卷第4期

页      面：610-613页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China,No.30540058,30770714 the Natural Science Foundation of Beijing of China,No.7052030 the Talents Foundation of Organization Department of the Beijing Municipal Committee in China the Beijing Science Plan Project Fund of China,No.Z0005187040191-1 the Research Foundation of Capital Medical Development of China,No.2007-2068 

主　　题：nerve regeneration brain injury repetitive transcranial magnetic stimulation motor dysfunction cerebral infarction NationalInstitute of Health Stroke Scale Barthel Index Fugl-Meyer Assessment neural regeneration 

摘      要：Low frequency （≤ 1 Hz） repetitive transcranial magnetic stimulation （rTMS） can affect the excitability of the cerebral cortex and synaptic plasticity. Although this is a common method for clinical treatment of cerebral infarction, whether it promotes the recovery of motor function remains controversial. Twenty patients with cerebral infarction combined with hemiparalysis were equally and randomly divided into a low frequency rTMS group and a control group. The patients in the low frequency rTMS group were given 1-Hz rTMS to the contralateral primary motor cortex with a stimulus intensity of 90% motor threshold, 30 minutes/day. The patients in the control group were given sham stimulation. After 14 days of treatment, clinical function scores （National Institute of Health Stroke Scale, Barthel Index, and Fugl-Meyer Assessment） improved significantly in the low frequency rTMS group, and the effects were better than that in the control group. We conclude that low frequency （1 Hz） rTMS for 14 days can help improve motor function after cerebral infarction.