Ghosts in the shell:identification of microglia in the human central nervous system by P2Y12 receptor

作     者：alexander mildner 

作者机构：max-delbrück center berlinGermany 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2017年第12卷第4期

页      面：570-571页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学] 

基　　金：supported by the Deutsche Forschungsgemeinschaft(DFG MI1328) 

主　　题：Ghosts in the shell identification of microglia in the human central nervous system by P2Y12 receptor 

摘      要：Microglia are the tissue resident macrophages of the brain and represent the sole immune population located in the parenchyma of the central nervous system （CNS）. These cells are hidden be-tween neurons, astrocytes as well as oligodendrocytes and account for only 5-10% of CNS cells. Even though microglia were already identified in 1913 by the Spanish neuroanatomist Ramon y Cajal and further seminally investigated by his student Pio del Rio Hortega,