Study on Spot Addressing and Segmentation Method for Microarray Image

作     者：LIU Quan-jin ZHU Xing-yue ZHAO Zhi-min 

作者机构：College of ScienceNanjing University of Aeronautics and Astronautics School of Physics & Electronic EngineeringAnqing Normal College 

出 版 物：《Chinese Journal of Biomedical Engineering(English Edition)》 (中国生物医学工程学报（英文版）)

年 卷 期：2016年第25卷第4期

页      面：139-148页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程] 

基　　金：National Natural Science Foundation of China grant number:61475071 Funding for Outstanding Doctoral Dissertation in NUAA grant number:BCXJ14-13 

主　　题：microarray image spot addressing foreground segmentation particle swarm optimization(PSO) algorithm 

摘      要：This paper presents a novel method of spot addressing and segmentation about the foreground segmentation of microarray image. In this paper,a spot addressing method based on particle swarm optimization(PSO),algorithm is proposed to have a further search for the center coordinate and radius of the spot whose region is determined by the projection method. Then,a foreground segmentation method is put forward to make the spot foreground segmentation based on the center coordinate and radius of the spot. The spot addressing and segmentation experiments on synthetic and real microarray images show that the proposed method is effective and feasible for the foreground segmentation of microarray image.