Facile synthesis of enzyme functional metal-organic framework for colorimetric detecting H_2O_2 and ascorbic acid

作     者：Cunji Gao Hongmei Zhu Jia Chen Hongdeng Qiu 

作者机构：Key Laboratory of Chemistry of Northwestern Plant ResourcesKey Laboratory for Natural Medicine of Gansu ProvinceLanzhou Institute of Chemical PhysicsChinese Academy of Sciences Institute of Microbiology and Biochemical PharmacySchool of PharmacyLanzhou University 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2017年第28卷第5期

页      面：1006-1012页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 

基　　金：the support of the Funds for Distinguished Young Scientists of Gansu(No.1506RJDA281) the top priority program of "One-Three-Five" Strategic Planning of Lanzhou Institute of Chemical Physics,CAS the Foundation for Sci&Tech Research Project of Gansu Province(No.1606RJYA307) 

主　　题：Metal organic frameworks Horseradish peroxidase H2O2 Ascorbic acid Colorimetric detection Biomimetic catalyst 

摘      要：In this work,a metal-organic frameworks material MIL-88 was prepared easily using solvent-thermal method,and was first found to have catalytic activities similar to those of biological enzymes such as catalase and *** material was characterized by XRD,SEM,TEM,EDX,FT-IR techniques and an N2 adsorption *** exhibited peroxidase-like activity through catalytic oxidation of the peroxidase substrate 3,3＇,5,5＇-tetramethylbenzidine（TMB） in the presence of H2O2,producing a blue-colored *** optimal conditions,the absorbance at 652 nm is linearly correlated with the concentration of H2O2 from 2.0×10^-6 mol/L to 2.03×10^-5 mol/L（R-2=0.981） with a detection limit of 5.62×10^-7 mol/L（S/N=3）.More importantly,a sensitive and selective method for ascorbic acid detection was developed using this material as a *** analytical method for ascorbic acid detection was observed to have a linear range from 2.57×10^-6 mol/L to 1.01×10^-5 mol/L（R-2=0.989） with a detection limit of 1.03×10^-6 mol/L（S/N=3）.This work suggests MOFs have advantages of preparing biomimetic catalysts and extends applications of the functional MOFs in the field of biosensor.