MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping

作     者：Meng-qi Liu Zhi-ye Chen Xiang-bing Bian Meng-yu Liu Shen-yuan Yu Lin Ma 

作者机构：Department of Radiology Chinese People's Liberation Army General Hospital 

出 版 物：《Chinese Medical Sciences Journal》 (中国医学科学杂志（英文版）)

年 卷 期：2015年第30卷第1期

页      面：34-36页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

基　　金：Supported by the National Natural Science Foundation of China(81171319) Nursery Fund of PLA General Hospital(13KMM41) 

主　　题：lateral geniculate body quantitative susceptibility mapping magnetic resonance imaging aging 

摘      要：Objective To investigate the changes of lateral geniculate body （LGB） in the normal aging brain using quantitative susceptibility mapping （QSM） technique. Methods Magnetic resonance （MR） phase and magnitude images were acquired from enhanced gradient echo T2 star weighted angiography sequence with 16 echoes on 3.0T MR system using the head coil with 32 channels. Morphology Enabled Dipole Inversion （MEDI） method was applied for QSM, and the susceptibility value of LGB was measured by region of interest （ROI） drawn manually on three orthogonal planes. Results LGB of the middle-aged group had a higher susceptibility value （0.16±0.05 ppm） than that of the youth group （0.12±0.05 pprn） and elderly group （0.13±0.03 ppm） （all P〈0.05）. Partial correlation analysis demonstrated that there was significantly positive correlation between susceptibility value and age in the youth group （r=0.71, P〈0.05）. Conclusion LGB could clearly be identified on QSM in the brain in vivo.