Androgens, Male Hypogonadism and Traumatic Brain Injury
Androgens, Male Hypogonadism and Traumatic Brain Injury作者机构：Centro de Neurociências Aplicadas (CeNAp) Hospital Universitário da Universidade Federal de Santa Catarina (HU-UFSC) Florianópolis Brazil Departamento de Clínica Médica Hospital Universitário da Universidade Federal de Santa Catarina (HU-UFSC) Florianópolis Brazil Departamento de Clínica Médica Hospital Universitário da Universidade Federal de Santa Catarina (HU-UFSC) Florianópolis Brazil Centro de Neurociências Aplicadas (CeNAp) Hospital Universitário da Universidade Federal de Santa Catarina (HU-UFSC) Florianópolis Brazil
出 版 物：《Open Journal of Endocrine and Metabolic Diseases》 (内分泌与新陈代谢疾病期刊（英文）)
年 卷 期：2014年第4卷第1期
页 面：13-23页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Traumatic Brain Injury Androgens Male Hypogonadism Treatment
摘 要：Traumatic brain injury (TBI) is a worldwide public health problem. Populations with a growing number of vehicles are experiencing many traumas and accidents. The highest-risk group is young men. Significant advances in neurosurgery and intensive therapy have resulted in increased survival rates of TBI patients. These higher survival rates, in turn, have led to an increasingly higher number of patients with neurological, cognitive, clinical, and social problems. This lack of knowledge about TBI has been called by some “the silent epidemic. In recent years, studies of patients with moderate and severe TBI are increasing. Glasgow Coma Scale ≤ 8 and abnormal pupils at admission are used to determine the prognosis of patients with moderate or severe TBI. Several biomarkers such as interleukins, thiobarbituric acid reactive species, and some hormones have been studied in an effort to aid prognosis. Testosterone plays a key role in men. Thus, an understanding of androgens in TBI is essential to follow these survivors of head trauma. This review will discuss the epidemiology of TBI, its association with male hypogonadism, and possible treatments.
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