泛昔洛韦分别联合干扰素γ、胸腺肽抗乙肝病毒疗效的临床观察
Observation on the Clinical Efficacy of Famcilovir Respectively Combined with Interferon- γ and Thymopentin in Treatment of Hepatitis B作者机构:中国·武警上海总队医院201103
出 版 物:《美国中华健康卫生杂志》 (U.S.CHINESE HEALTH AND HYGIEME JOURNAL)
年 卷 期:2003年第6卷第2期
页 面:54-55页
学科分类:1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
摘 要:Objective To observe the efficacy of anti - HBV DNA medicine and different combina-tion. Methods 170 ASC CHB patients were categorized into two groups( group Ⅰ, hays 65 patients, they were randomised to receive Famcilovir combine with Interferon- γ; group Ⅱ , hays 105 patients they were randomised to receive Famcilovir combine with Thymopentin), the controls treat by Interferon - a2b. Re-stilt 53.3 % of the group Ⅰ and 38.3 % of the group Ⅱ had undetectable serum HBV DNA, compared with 28.6% in the control group: the people diminition 10^2 coples/ml,38.8% of whom are in the group Ⅰ ,49.5% whom are in the group Ⅱ ,compared with 28.6% in control group(P 0.025) ;After treat-ment, they also go down more obviously in HBeAg HbsAg and the group Ⅰ is better than the group Ⅱ .Conclusion Conbination of two different medicine is a useful method, and it may indicate that much time is neccssary to receive anti- HBV DNA patients, especially to theose accept immune treatment.