A rare case of langerhans cell histiocytosis of the gastrointestinal tract

作     者：Uday Shankar Monika Prasad Om P Chaurasia 

作者机构：Internal MedicineMount Sinai School of Medicine at Queens Hospital CenterJamaicaNY 11432United States Department of MedicineUniversity of CaliforniaIrvineCA 92697United States 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2012年第18卷第12期

页      面：1410-1413页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：细胞增生 细胞组织 胃肠道 全身性疾病 嗜酸性粒细胞 病理检查 免疫组化染色 LCH 

摘      要：Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the proliferation of specialized,bone marrow-derived langerhans cells and mature *** clinical spectrum ranges from an acute,fulminant,disseminated disease called LettererSiwe disease to solitary or few,indolent and chronic lesions of the bone or other organs called eosinophilic *** of the gastrointestinal tract is very rare in *** present the case of a 53-yearold woman referred by her primary care physician for a screening colonoscopy.A single sessile polyp,measuring 4 mm in size,was found in the *** examination revealed that the lesion was relatively well circumscribed and comprised mainly a mixture of polygonal cells with moderate-to-abundant pink slightly granular *** nuclei within these cells had frequent grooves and were occasionally *** staining was positive for CD1a which confirmed the diagnosis of *** further workup,there was no evidence of involvement of any other *** follow up colonoscopy one year later,there was no evidence of disease *** of the published literature revealed that LCH presenting as solitary colonic polyp is ***,with the increas-ing rates of screening colonoscopy,more colonic polyps may be identified as LCH on *** underscores the importance of recognizing this rare condition and ensuring proper follow-up to rule out systemic disease.