Attributable Causes of Cancer in China:Fruit and Vegetable

作     者：Hui-juan Xiao Hao Liang Jian-bing Wang Cheng-Yu Huang Wen-qiang Wei Mathieu Boniol You-lin Qiao Paolo Boffetta 

作者机构：Department of Nutrition and Food Hygiene West China School of Public Health Sichuan University Chengdu 610041 China Departments of Cancer Epidemiolo gy Cancer Institute Chinese Academy of Medical Sciences Beijing 100021 China Department of Epidemiology and Statistics Institute of Basic Medical Sciences Chinese Academy of Medical Sciences ＆School of Basic Medicine Peking Union Medical College Beijing 100005 China International Prevention Research Institute Lyon 69008 France The Tisch Cancer Institute Mount Sinai School of Medicine New York NY 10029 USA Nutrition Department Tianjin Third Central Hospital Tianjin 300170 China 

出 版 物：《Chinese Journal of Cancer Research》 (中国癌症研究（英文版）)

年 卷 期：2011年第23卷第3期

页      面：171-176页

核心收录：

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1002[医学-临床医学] 08[工学] 09[农学] 0902[农学-园艺学] 090202[农学-蔬菜学] 

基　　金：supported by International Agency for Research on Cancer (Lyon  France) grant CRA No GEE/08/19 

主　　题：Fruit Vegetable Cancer Population attributable fraction China 

摘      要：Objective：To provide an evidence-based and consistent assessment of the burden of cancer attributable to inadequate fruit and vegetable intake in China in 2005.Methods：The proportions of cancers attributable to low consumption of vegetable and fruit were calculated separately to estimate the burden of related cancers for the year 2005 in China.Data on the prevalence of exposure were derived from a Chinese nutrition and health survey.Data on relative risks were mainly derived from meta-analysis.Attributable fractions were calculated based on the counterfactual scenario which was a shift in the exposure distribution.Results：The total cancer burden attributable to inadequate consumption of fruit was up to 233,000 deaths （13.0% of all cancers） and 300,000 cases （11.6% of all cancers） in 2005.Increasing consumption of vegetable to the highest quintile could avoid total cancer deaths and cases by 3.6% （64,000 persons） and 3.4% （88,000 persons）.The contributions to cancer burden were higher in rural areas than in urban areas.They have greater influence on men than on women.The largest proportions of cancer burden attributable to low fruit and vegetable intake were for oral and pharyngeal cancers.Conclusion：This study showed that inadequate intake of fruit and vegetable makes a significant contribution to the cancer burden.Increasing consumption of fruit and vegetable could prevent many cancer deaths and save many lives.Promoting the consumption of fruit and vegetable is an important component in diet-based strategies for preventing cancer.