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Prevalence of viral HBV and HCV among different group patients in Gujrat Pakistan

Prevalence of viral HBV and HCV among different group patients in Gujrat Pakistan

作     者:Muhammad Irshad Muhammad Naem Raza Zahid Anwar Nadia Ikram Amber Afroz Hafiz Muhammad Nasir Iqbal 

作者机构:Department of Biochemistry and Molecular Biology University of Gujrat Pakistan Department of Biochemistry NSMC University of Gujrat Pakistan Department of Chemistry and Biochemistry University of Agriculture Faisalabad Pakistan 

出 版 物:《Advances in Bioscience and Biotechnology》 (生命科学与技术进展(英文))

年 卷 期:2012年第3卷第4期

页      面:423-436页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:HBV HCV Liver Inflammation LFTs ELISA ALP Bilirubin 

摘      要:In this study we analyzed blood samples collected from 400 high risk patients for the prevalence of an inflammatory viral disease hepatitis B virus (HBV) and hepatitis C virus (HCV) with the help of standard kit assay and Enzyme-linked immunosorbent assay (ELISA). All the samples were selected randomly from the various places of District Gujrat, Pakistan. All the selected cases were first divided into four groups according to the age and sex (Group 1, Male below age 35 years;Group 2, Male above age 35 years;Group 3, Female below age 35 years;Group 4, Female above age 35 years), each group was comprised of 100 individual patients and analyzed for different parameters for the presence of HBV and HCV in comparison with positive and negative controls. The prevalence of HBV and HCV was higher in groups 2 (22%) and 4 (39%) respectively. Assay profile revealed that the incidence of HCV was higher in female patients as compare to the male patients. The present study indicates that more than 60% of the cirrhosis and hepatocellular carcinoma in the Region is attributable to hepatitis B virus (HBV) or hepatitis C virus (HCV) infection.

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