Features of Glucose Metabolism in Pleomorphic Hyalinizing Angiectatic Tumor (PHAT)

作     者：Po-Jui Chang Cher-Wei Liang Ching-Huei Kung Ching-Shui Huang Chung-Huei Hsu 

作者机构：Department of Nuclear Medicine Taipei Medical University Hospital Taipei Taiwan Department of Pathology Cathay General Hospital Taipei Taiwan Department of Radiology Taipei Medical University Hospital Taipei Taiwan Department of Surgery Cathay General Hospital Taipei Taiwan 

出 版 物：《Advances in Molecular Imaging》 (分子影像学（英文）)

年 卷 期：2014年第4卷第1期

页      面：11-13页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：PHAT FDG-PET Sarcoma 

摘      要：Pleomorphic Hyalinizing Angiectatic Tumor (PHAT) is a rare mesenchymal neoplasma. It is a pathological term describing a heterogeneous group of neoplasms of undetermined tumorigenesis and undefined malignancy. Based only on the morphological findings of histopathology, the biological potential of the tumor is indeterminate. Determination of glucose metabolism using FDG-PET revealed mildly increased FDG uptake in the tumor. We propose that FDG accumulation in the ectatic vessel, increased uptake of the pleomorphic cells and/or associated inflammatory cells, and increased permeability of the stroma lead to the imaging feature.