Breast Cancer Survival in Cameroon: Analysis of a Cohort of 404 Patients at the YaoundéGeneral Hospital

作     者：Jean Dupont Kemfang Ngowa Jean Marie Kasia Jean Yomi Achille Nkigoum Nana Anny Ngassam Irenée Domkam Zacharie Sando Paul Ndom 

作者机构：Department of Gynecology and Obstetrics Yaoundé General Hospital Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaoundé Cameroon Department of Radiation Therapy Yaoundé General Hospital Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Chantal Biya International Reference Centre for Research on HIV/AIDS Prevention and Management Yaoundé Cameroon Department of Morphological Sciences Yaoundé General Hospital Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Oncology Division Yaoundé General Hospital Yaoundé Cameroon 

出 版 物：《Advances in Breast Cancer Research》 (乳腺癌（英文）)

年 卷 期：2015年第4卷第2期

页      面：44-52页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Survival Breast Cancer Developing Countries 

摘      要：This study aimed to estimate the survival rate of breast cancer in a group of patients followed up at the Yaoundé General Hospital in Cameroon. A retrospective review of records of patients managed for breast cancer between 1995 and 2007 was carried out at the Yaoundé General Hospital. Survival analysis was carried out with survival defined as the time between the date of unequivocal diagnosis of cancer and the date of last follow-up or death. Survival curves were plotted in R.3.1.1 software. Mean age of the patients was 47.5 ± 12.36 years. Most of the patients (67.9%) presented with advanced breast cancer disease (stage III and IV). Overall patient survival rate was 30% at 5 years and 13.2% at 10 years. Median overall survival time was 2 (1.9 - 3) years. There was a correlation between survival and the stage of disease. The highest survival rates were recorded in stages I and II while the lowest rates were recorded in stage IV. There was no statistically significant difference in survival among the age groups (p = 0.15). Overall survival rates of breast cancer are 30% at 5 years and 13.2% at 10 years among Cameroonian patients and are lower compared with 90% and 82% respectively at 5 years and 10 years in some developed countries.