Efferocytosis in Retinoblastoma

作     者：Dipankar Das Harsha Bhattacharjee Kasturi Bhattacharjee Prerana S. Tahiliani Pankaj Bhattacharyya Manabjyoti Barman Sumita Sarma Barthakur Panna Deka Apurba Deka Rajashree Paul 

作者机构：Sri Sankaradeva Nethralaya Guwahati India 

出 版 物：《Journal of Cancer Therapy》 (癌症治疗（英文）)

年 卷 期：2013年第4卷第9期

页      面：1443-1447页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Retinoblastoma Apoptosis Efferocytosis Vesicles Undifferentiated 

摘      要：Retinoblastoma has varied presentations. As age advances in retinoblastoma, the undifferentiated tumour is the common appearance. Apoptosis in retinoblastoma in an untreated case can give us a clue about the tumour biology. Efferocytosis in intraocular tumour is a new concept which was seen in an enucleated eyeball specimen in a 4-year-old boy. Effective efferocytosis can be conceptualized for new pharmacodynamics application for anti-cancer drugs. We present a rare case of retinoblastoma with efferocytosis in retinal pigment epithelium and interesting apoptotic changes.