Universal RNA editing in a human liver at the fetal stage

作     者：Dong Liu Cong Liu Xiyin Wang Sigurdur Ingvarsson Huiping Chen 

作者机构：Department of Medical Genetics Tongji Medical College Huazhong University of Science and Technology Wuhan China Institute for Experimental Pathology and Faculty of Medicine University of Iceland Keldur Iceland 

出 版 物：《Open Journal of Genetics》 (遗传学期刊（英文）)

年 卷 期：2012年第2卷第3期

页      面：163-166页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：RNA Editing miRNA rRNA mRNA miscRNA Fetal Liver 

摘      要：It is known that RNA editing occurs in human cells, which can change the information transmission from DNA to RNA and proteins. Most previous studies have focused on editing of the mRNAs. Here we reported that several kinds of RNAs, including miRNA, rRNA, mRNA, miscRNA and unknown RNA, exhibited base editing in a human fetal liver. Several editing types are displayed. Our data reveals that RNA editing may occur in different species of RNAs.