Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles
Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles作者机构:不详
出 版 物:《International Journal of Organic Chemistry》 (有机化学国际期刊(英文))
年 卷 期:2011年第1卷第3期
页 面:78-86页
主 题:1-Aroyl-2-Styrylsulfonylethene 1 3-Dipolar Cycloaddition Chloramine-T Antimicrobial Activity
摘 要:A new and novel class of bis(heterocycles) viz., bis pyrroles, pyrrolyl pyrazoles and pyrrolyl isoxazoles are prepared from 1-aroyl-2-styrylsulfonylethenes by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, diazomethane, nitrile imines and nitrile oxides. The lead compounds are screened for antimicrobial activity.