Stereoselective Synthesis of <i>cis</i>-Substituted-3’-anilino-2’, 3’-dihydro-4-2’-benzo[<i>b</i>]furanylcoumarins via Intramolecular Aldol Reactions
Stereoselective Synthesis of <i>cis</i>-Substituted-3’-anilino-2’, 3’-dihydro-4-2’-benzo[<i>b</i>]furanylcoumarins via Intramolecular Aldol Reactions作者机构:P. G. Department of Chemistry Karnatak University Dharwad India P. G. Department of Physics University of Jammu Jammu Tawi India
出 版 物:《International Journal of Organic Chemistry》 (有机化学国际期刊(英文))
年 卷 期:2012年第2卷第1期
页 面:44-48页
主 题:Aldol Reaction Stereoselective Intramolecular Mild Base 4-Bromomethylcoumarins Dihydrobenzofurans
摘 要:The present study reports the reaction of 4-bromomethylcoumarins with salicylidineaniline in acetone with two equivalents of potassium carbonate resulted in the formation of title compounds at room temperature via intramolecular aldolization. The obtained compound is thermodynamically and kinetically stable with highly stereoselective and excellent yield.