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Effective Use of Sugammadex for Incomplete Pyridostigmine Reversal of Muscle Relaxation by Rocuronium: A Case Report

Effective Use of Sugammadex for Incomplete Pyridostigmine Reversal of Muscle Relaxation by Rocuronium: A Case Report

作     者:Hee Jong Lee Kyo Sang Kim Ji Seon Jeong Sung Hwan Choi Kyu Nam Kim 

作者机构:Department of Anesthesiology and Pain Medicine Hanyang University Hospital Seoul South Korea 

出 版 物:《Open Journal of Anesthesiology》 (麻醉学期刊(英文))

年 卷 期:2013年第3卷第9期

页      面:393-395页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Pyridostigmine Residual Block Rocuronium Sugammadex 

摘      要:Anticholinesterase does not allow adequate reversal of the deep neuromuscular blockade (NMB) achieved using high doses of relaxants. A 71-year-old female patient (weight 70 kg, height 169 cm) was scheduled for a transurethral resection of a bladder tumor under general anesthesia. We administered rocuronium 30 mg (0.43 mg/kg) for tracheal intubation due to an estimated short surgical time. During the operation, an additional rocuronium 10 mg was injected. The surgical procedure ended abruptly 10 minutes after receiving the last dose of rocuronium. At the end of surgery, the patient received pyridostigmine as a reversal. However, residual NMB persisted, and neuromuscular monitoring did not show the expected degree of recovery. Sugammadex 2 mg/kg was used, and the patient experienced complete reversal from NMB in just 2 min.

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