Langerhans cell histiocytosis masquerading as acute appendicitis: Case report and review
Langerhans cell histiocytosis masquerading as acute appendicitis: Case report and review作者机构：Department of SurgeryHarbor-UCLA Medical Center Department of PathologyHarbor-UCLA Medical Center
出 版 物：《World Journal of Gastrointestinal Endoscopy》 (世界胃肠内镜杂志（英文版）（电子版）)
年 卷 期：2017年第9卷第3期
页 面：139-144页
学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题：Langerhans cell histiocytosis Adult histiocytosis Appendicitis Gastrointestinal histiocytosis Right lower quadrant pain
摘 要：Langerhans cell histiocytosis(LCH) is a rare syndrome characterized by unifocal,multifocal unisystem,or disseminated/multi-system disease that commonly involves the bone,skin,lymph nodes,pituitary,or sometimes lung(almost exclusively in smokers) causing a variety of symptoms from rashes and bone lesions to diabetes insipidus or pulmonary *** present a previously unreported case of gastrointestinal LCH as well as a novel characteristic lesion affecting the colon of a young woman who presented with signs and symptoms mimicking acute on chronic *** analysis of appendectomy specimen and nodular specimens on colonoscopy demonstrated S-100,CD1a,and langerin *** patient underwent systemic chemotherapy with cytarabine and demonstrated excellent response to therapy.
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